Why liver transplant required?

 

Liver transplant is recommended when patient’s liver failed to perform its regular functions. In liver transplant patient’s damaged or diseased liver is replaced with  a part of healthy liver from the living donor or deceased donor.

Liver is such an organ in our body as important as our heart and brain that we cannot live without liver more than 2-3 days. So when it fails to perform its duty patient needs a transplantation of liver to survive.

There are two types of liver failure: Acute liver failure and chronic liver failure. Acute liver failure means sudden liver failure. Drug induced liver injury is the common cause of acute liver failure, i.e Liver Failure due to side effect of  some medicines.

Chronic liver failure is the long term progress of disease over  months or  years . most often it is the result of cirrhosis where liver tissue has scars and without replacing this scar tissues with healthy one, liver cannot function adequately. 

There are many reasons for liver failure.

successChronic hepatitis with cirrhosis

successPrimary biliary cirrhosis where immune system inappropriately attacks the bile ducts which ends in liver failure

successScarring and narrowing bile ducts inside and outside of the liver which creates a back- up of bile in liver which cases liver failure.

successMalformation of bile ducts.

successAlcoholism

successWilson disease which is inherited disease which involves abnormal depositions of the copper throughout the body

successAbnormal accumulation of alpha 1 in liver resulting cirrhosis

successLiver cancer.

  Signs and symptoms of liver failure are jaundice, fatigue, weakness, loss of appetite, nausea, weight loss, muscle loss, itching, bruising and bleeding easily ( because blood does not clot), bleeding in the stomach, vomiting blood, passing black stools,  ascites i.e. buildup of the fluid in the abdomen, forgetfulness or confusion. These all indicates liver failure and patient needs treatment for that.

 

 

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